• Xunwu Hu, Sona Rani Roy, Chengzhi Jin, Guanying Li, Qizheng Zhang, Natsuko Asano, Shunsuke Asahina, Tomoko Kajiwara, Atsushi Takahara, Bolu Feng, Kazuhiro Aoki, Cehnjie Xu, Ye Zhang* “Control Cell Migration by Engineering Integrin Ligand Assembly” Nature Communications, 2022, 13:5002
  • Jiaqi Song, Qizheng Zhang, Guanying Li,* Ye Zhang* "Constructing ECM-like Structure on the Plasma Membrane via Peptide Assembly to Regulate the Cellular Response", Langmuir, 2022, 38, 8733-8747.
  • Enming Du, Yunlan Tang, Qizheng Zhang, Zongming Song,* Ye Tao,* and Ye Zhang* “Enhancing the Cellular Uptake of Macromolecules via Enzyme-Instructed Self-Assembly”, Langmuir, 2022, 38, 4364-4370
  • Liang Shao, Shichang Liu, Guanying Li,* Ye Zhang* “Capture Phosphates via Peptide Self-assembly to Construct Templates Assisting Mineralization” ChemNanoMat, 2022, 8, e202100542.


  • Xunwu Hu, Ye Zhang* “Developing Biomaterials to Mediate the Spatial Distribution of Integrins” Biophysics Reviews, 2021, 2, 041302.
  • Dingze Mang, Sona Rani Roy, Qizheng Zhang, Xunwu Hu, Ye Zhang*“Heparan-Sulfate-Instructed Self-Assembly Selectively Inhibits Cancer Cell Migration” ACS Applied Materials & Interfaces, 2021, 13, 17236-17242.
  • Guanying Li, Xunwu Hu, Xia Wu, Ye Zhang* “Microtubule-Targeted Self-Assembly Triggers Prometaphase-Metaphase Oscillations Suppressing Tumor Growth” Nano Letters, 2021, 21, 3052-3059.

  • Chengzhi Jin, Guanying Li, Xia Wu, Jiangpin Liu, Weijun Wu, Toshio Sasaki, Hui Chao,* and Ye Zhang* “Robust Packing of a Self-Assembling Iridium Complex via Endocytic Trafficking for Long-term Lysosome Tracking” Angew. Chem. Int. Ed., 2021, 60, 7597-7601.
  • Guanying Li, Xunwu Hu, Pingping Nie, Dingze Mang, Shi Jiao, Shijin Zhang, Sona Rani Roy, Sachie Yukawa, Shunsuke Asahina, Hiroaki Sugasawa, William Cortes, Zhaocai Zhou* and Ye Zhang* “Lipid-raft-targeted Molecular Self-assembly Inactivates YAP to Suppress Ovarian Cancer Growth” Nano Letters, 2021, 21, 747-755.
  • Xia Wu, Xunwu Hu, Ye Zhang* “Regulate Cellular Responses via Molecular Assembly in Cell Milieu for Cancer Therapy” Chemistry Letters, 2021, 50 (Commemorative Highlight Review), 405-410.


  • Guanying Li, William Cortes, and Ye Zhang* “Chemical Oscillation and Morphological Oscillation in Catalyst-embeded Lyotropic Liquid Crystalline Gels” Frontiers in Chemistry, (invited contribution), 2020, (doi.org/10.3389/fchem.2020.583165).
  • Shijin Zhang, and Ye Zhang* “Promote Dual-Targeting Anticancer Effect by Regulating the Dynamic Intracellular Self-Assembly” ACS Applied Materials & Interfaces, 2020, 37, 41105-41112.
  • Jiaqing Wang, Weiyi Tan, Guanying Li, Difei Wu, Hongjian He, Jiashu Xu, Meihui Yi, Ye Zhang, S. Ali Aghvami, Seth Fraden, Bing Xu* “Enzymatic Insertion of Lipids Increases Membrane Tension for Inhibiting Cancer Cells” Chem. Eur. J. 2020, 26, 15116-15120.
  • Shijin Zhang, William Cortes, and Ye Zhang* “Constructing Cross-linked Nanofibrous Scaffold via Dual-Enzyme-Instructed Hierarchial Assembly” Langmuir, 2020, 36, 6261-6267.
  • Sona Rani Roy, Guanying Li, Xunwu Hu, Shijin Zhang, Sachie Yukawa, Enming Du, and Ye Zhang* “Integrin and Heparan Sulfate Dual-targeting Peptide Assembly Suppresses Cancer Metastasis” ACS Applied Materials & Interfaces, 2020, 17, 19277-19284.
  • Dingze Mang, Sona Rani Roy, Hong Huat Hoh, Xia Wu, Jiahao Zhang, Chengzhi Jin, and Ye Zhang* “Self-Assembly of Integrin Ligands on the Apical Membrane Inhibits the Migration of Glioma Cells” Langmuir, 2020, 14, 3750-3757.
  • Shijin Zhang, William Cortes, Toshio Sasaki, Shunsuke Asahina, Asano Natsuko, Qizheng Zhang, and Ye Zhang* "Mechanoresponsive Alignment of Molecular Self-assembled Negatively Charged Nanofibrils" ACS Applied Bio Materials. 2020, 3, 1698-1704.


  • Shijin Zhang, Xunwu Hu, Dingze Mang, Toshio Sasaki, and Ye Zhang* "Self-delivery of N-hydroxylethyl Peptide Assemblies to the Cytosol Inducing Endoplasmic Reticulum Dilation in Cancer Cells "  Chem. Commun. 2019, 55, 7474-7477.
  • Enming Du, Xunwu Hu, Guanying Li, Shijin Zhang, Dingze Mang, Sona Roy, Toshio Sasaki, and Ye Zhang* "Self-Assembly-Directed Cancer Cell Membrane Insertion of Synthetic Ananlogues for Permeability Alteration" Langmuir2019, 35, 7376 - 7382.


  • Wei Ji, Shijin Zhang, Sachie Yukawa, Shogo Onomura, Toshio Sasaki, Kunichi Miyazawa, and Ye Zhang* "Regulate Higher-order Organization through the Synergy of Two Self-sorted Assemblies" Angew. Chem. Int. Ed. 2018, 57, 3636-3640.


  • Wei Ji, Shijin Zhang, Gerogy A. Filonenko, Guanying Li, Toshio Sasaki, Chuanliang Feng* and Ye Zhang* "Co-Organizing Synthesis of Heterogeneous Nanostructure through Photo-Cleavage of Pre-Stabilized Self-Assemblies"  Chem. Commun. 2017, 53, 4702-4705.
  • Guanying Li, Toshio Sasaki, Shunsuke Asahina, Michael C. Roy, Toshiaki Mochizuki, Koji Koizumi, and Ye Zhang*“Patching of Lipid Rafts by Molecular Self-Assembled Nanofibrils Suppresses Cancer Cell Migration” Chem. 2017, 2, 283-298.
  • Enming Du, Xunwu Hu, Sona Roy, Peng Wang, Kieran Deasy, Toshiki Mochizuki and Ye Zhang* "Taurine-Modified Ru(II)-Complex Targets Cancerous Brain Cells for Photodynamic Therapy”, Chem. Commun. 2017, 53, 6033-6036.

2016 & before

    • Yunhui Zheng.; Guanying Li; Ye Zhang* "Organometallic Hydrogels" ChemNanoMat, 2016, 2, 364-375.
    • Qingcong Wei, Mengchi Xu, Chuanan Liao, Qing Wu, Mingyu Liu, Ye Zhang*, Chengtie Wu*, Qigang Wang* "Printable hybrid hydrogel by dual enzymatic polymerization with superactivity" Chemical Science, 2016,7, 2748.
    • Ye Zhang; Zhou, N.; Shi, J. F.; Pochapsky, S. S.; Pochapsky, T. C.; Zhang, B.; Zhang, X. X.; Xu, B.* “Unfolding a molecular trefoil derived from a zwitterionic metallopeptide to form self-assembled nanostructures” Nature Commun. 2015, 6, 6165.
    • Shi, J. F.; Du, X. W.; Huang, Y. B.; Zhou, J.; Yuan, D.; Wu, D. D.; Ye Zhang; Haburcak, R.; Eptein, I. R.*; Xu, B.* “Ligand-Receptor Interaction Catalyzes the Aggregation of Small Molecules to Induce Cell Necroptosis” J. Am. Chem. Soc. 2015, 137, 26-29.
    • Park, S.; Kim, D.; Ko, S. Y.; Park, J-O., Akella S., Xu, B., Ye Zhang; Fraden, S.* “Controlling uniformity of photo-polymerized microscopic hydrogels” Lab on a Chip. 2014, 14, 1551-1563.
    • Ye Zhang; Zhou, N.; Kim, D.; Fraden, S.*; Epstein, I. R.*; Xu, B.* “Giant Volume Change of Active Gels under Continuous Flow” J. Am. Chem. Soc., 2014, 136, 7341-7347.
    • Ye Zhang; Zhou, N.; Akella, S.; Kuang, Y.; Kim, D.; Schwartz, A.; Bezpalko, M.; Foxman, B. M.; Fraden, S.; Epstein, I. R.*; Xu, B.* “Active Cross-linkers that Lead to Active Gels” Angew. Chem. Int. Ed. 2013, 52, 6944-6948.
    • Ye Zhang; Zhou, R.; Shi, J.; Zhou, N.; Epstein, I. R.; Xu, B.* “Post-Self-Assembly Cross-Linking to Integrate Molecular Nanofibers with Copolymers in Oscillatory Hydrogels” J. Phys. Chem. B, 2013, 117, 6566-6573.
    • Ye Zhang; Zhang, B.; Kuang, Y.; Gao, Y.; Shi, J.; Zhang, X. X.; Xu, B.* “A Redox Responsive, Fluorescent Supramolecular Metallohydrogel Consists of Nanofibers with Single-Molecule Width” J. Am. Chem. Soc., 2013, 135, 5008-5011.
    • Kuang, Yi.; Yuan, D.; Ye Zhang; Du, X. W.; Xu, B.* “Interactions between cellular proteins and morphologically different nanoscale aggregates of small molecules” RSC Advances, 2013, 3, 7704-7707.
    • Yang, Z. M.; Kuang, Y.; Li, X. M.; Zhou, N.; Ye Zhang; Xu, B.* “Supramolecular hydrogel of kanamycin selectively sequesters 16S rRNA” Chem. Commun. 2012, 48, 9257-9259.
    • Ye Zhang; Li, N.; Delgado, J.; Zhou, N.; Yoshida, R.; Fraden, S.; Epstein, I. R.*; Xu, B.* “Structural modulation of self-oscillating gels: Changing the proximity of the catalyst to the polymer backbone to tailor chemomechanical oscillation” Soft Matter, 2012, 8, 7056-7061.
    • Ye Zhang; Li, N.; Delgado, J.; Gao, Y.; Kuang, Y.; Fraden, S.; Epstein, I. R.*; Xu, B.* “Post-Self-Assembly Crosslinking of Molecular Nanofibers for Oscillatory Hydrogels” Langmuir, 2012, 28, 3063-3066.
    • Delgado, J.; Ye Zhang; Xu, B.; Epstein, I. R. “Terpyridine- and Bipyridine-Based Ruthenium Complexes as Catalysts for the Belousov-Zhabotinsky Reaction” J. Phys. Chem. A, 2011, 115, 2208-2215.
    • Shi, J. F.; Gao, Y.; Ye Zhang; Pan, Y.; Xu, B.* “Calcium Ions to Crosslink Supramolecular Nanofibers to Tune the Elasticity of Hydrogels over Orders of Magnitude” Langmuir, 2011, 27, 14425-14431.
    • Ye Zhang; Yousef, Y. A.; Li, H.; Melø, T. B.; Naqvi, K. R.* “Comparison of the photochemical behaviors of α-tocopherol and its acetate in organic and aqueous micellar solutions” J. Phy. Chem. A. 2011, 29, 8242-8247.
    • Ye Zhang, Yi Kuang, Yuan Gao, Bing Xu* “Versatile Small Molecule Motifs for Self-assembly in Water and Formation of Biofunctional Supramolecular Hydrogels” Langmuir, 2011, 27, 529-537.
    • Yuan Gao, Fan Zhao, Qi Wang, Ye Zhang, Bing Xu* “Small Peptide Nanofibers as the Matrices of Molecular Hydrogels for Mimicking Enzymes and Enhancing the Activity of Enzymes” Chem. Soc. Rev. 2010, 39, 3425-3433.
    • Dai, W-M.*; Li, Y.; Ye Zhang; Yue, C.; Wu, J. “Generation of an Aromatic Amide-Derived Phosphane (Aphos) Library by Self-Assisted Molecular Editing and Applications of Aphos in Room-Temperature Suzuki-Miyaura Reactions” Chem. Eur. J. 2008, 14, 5538-5554.
    • Dai, W-M.*; Ye Zhang. “A Family of Simple Amide-Derived Air-Stable P, O-Ligands for Suzuki Cross-Coupling of Unactivated Aryl Chlorides” Tetrahedron Lett. 2005, 46, 1377-1381.
    • Dai, W-M.*; Li, Y.; Ye Zhang; Lai, K. W.; Wu, J. “A Novel Class of Amide-Derived Air-Stable P, O-Ligands for Suzuki Cross-Coupling at Low Catalyst Loading” Tetrahedron Lett. 2004, 45, 1999-2001.
    • W-M.*; Zhang, Y.; Ye Zhang. “Synthesis of Atropisomeric 2,8-Dioxygenated N, N-Diisopropyl-1-naphthamides via Kinetic Resolution under the Sharpless Asymmetric Dihydroxylation Conditions” Tetrahedron: Asymmetry 2004, 15-525-535.
    • Dai, W-M.*; Yeung, K. Y.; Liu, J-T.; Ye Zhang; Williams, I. D. “A Novel Class of Nonbiaryl Atropisomeric P, O-Ligands for Palladium-Catalyzed Asymmetric Allylic Alkyation” Org. Lett. 2002, 4, 1615-1618.


    Ye Zhang, Bing Xu.

    “Polymeric Materials Having Active Cross-linkers, Methods for Making Them, and Use Thereof”

    US Patent 43022.0100.


    Book & Book Chapter

    • Soft Nanomaterials (org/10.1142/11300) World Scientific Series in Nanoscience and Nanotechnology: Volume 19, 2020, Editied by Ye Zhang and Bing Xu.
    • Ye Zhang, and Bing Xu* “Superactivity of Enzymes in Supramolecular Hydrogels” in Proteins in Solution and at Interfaces: Methods and Applications in Biotechnology and Materials Science. Wiley, 2013, ISBN:9780470952511.

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